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Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer

Similarly to the Wnt protein palmitoyltransferase, porcupine (PPN) is essential to the activation of the Wnt/β-catenin signaling pathway. However, little is known about the role of PPN activity in human gastric cancer, one of the most common causes of cancer-related mortality. Real-time quantitative...

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Detalles Bibliográficos
Autores principales: MO, MIN-LI, LI, MENG-RU, CHEN, ZHAO, LIU, XING-WEI, SHENG, QING, ZHOU, HAI-MENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678880/
https://www.ncbi.nlm.nih.gov/pubmed/23761839
http://dx.doi.org/10.3892/ol.2013.1256