Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy

Numerous studies have reported widespread synaptic dysfunction or loss in early stages of both Alzheimer disease (AD) patients and animal models; it is widely accepted that synapse loss is the major structural correlate of cognitive dysfunction. Elucidation of the changes that may affect synapses is...

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Detalles Bibliográficos
Autores principales: Alonso-Nanclares, Lidia, Merino-Serrais, Paula, Gonzalez, Santiago, DeFelipe, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neuropathologists 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678882/
https://www.ncbi.nlm.nih.gov/pubmed/23584198
http://dx.doi.org/10.1097/NEN.0b013e31828d41ec

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678882/
https://www.ncbi.nlm.nih.gov/pubmed/23584198
http://dx.doi.org/10.1097/NEN.0b013e31828d41ec

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