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Casticin induces ovarian cancer cell apoptosis by repressing FoxM1 through the activation of FOXO3a

Casticin, a polymethoxyflavone, is reported to have anticancer activities. The aim of the present study was to examine the molecular mechanisms by which casticin induces apoptosis in ovarian cancer cells. The human ovarian cancer cell lines SKOV3 and A2780 were cultured in vitro. Various molecular t...

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Detalles Bibliográficos
Autores principales: JIANG, LING, CAO, XIAO-CHENG, CAO, JIAN-GUO, LIU, FEI, QUAN, MEI-FANG, SHENG, XI-FENG, REN, KAI-QUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678892/
https://www.ncbi.nlm.nih.gov/pubmed/23761826
http://dx.doi.org/10.3892/ol.2013.1258