Deficiency of Leishmania Phosphoglycans Influences the Magnitude but Does Not Affect the Quality of Secondary (Memory) Anti-Leishmania Immunity

Despite inducing very low IFN-γ response and highly attenuated in vivo, infection of mice with phosphoglycan (PG) deficient Leishmania major (lpg2-) induces protection against virulent L. major challenge. Here, we show that mice infected with lpg2- L. major generate Leishmania-specific memory T cell...

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Detalles Bibliográficos
Autores principales: Liu, Dong, Okwor, Ifeoma, Mou, Zhirong, Beverley, Stephen M., Uzonna, Jude E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679009/
https://www.ncbi.nlm.nih.gov/pubmed/23776605
http://dx.doi.org/10.1371/journal.pone.0066058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679009/
https://www.ncbi.nlm.nih.gov/pubmed/23776605
http://dx.doi.org/10.1371/journal.pone.0066058

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