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Impaired Glucose Tolerance in a Mouse Model of Sidt2 Deficiency

Sidt2 was identified as a novel integral lysosomal membrane protein recently. We generated global Sidt2 knockout mice by gene targeting. These mice have a comparatively higher random and fasting glucose concentration. Intraperitoneal and oral glucose tolerance tests in Sidt2 knockout mice indicated...

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Detalles Bibliográficos
Autores principales: Gao, Jialin, Gu, Xuefan, Mahuran, Don J., Wang, Zhugang, Zhang, Huiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679015/
https://www.ncbi.nlm.nih.gov/pubmed/23776622
http://dx.doi.org/10.1371/journal.pone.0066139