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Impaired Glucose Tolerance in a Mouse Model of Sidt2 Deficiency
Sidt2 was identified as a novel integral lysosomal membrane protein recently. We generated global Sidt2 knockout mice by gene targeting. These mice have a comparatively higher random and fasting glucose concentration. Intraperitoneal and oral glucose tolerance tests in Sidt2 knockout mice indicated...
Autores principales: | Gao, Jialin, Gu, Xuefan, Mahuran, Don J., Wang, Zhugang, Zhang, Huiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679015/ https://www.ncbi.nlm.nih.gov/pubmed/23776622 http://dx.doi.org/10.1371/journal.pone.0066139 |
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