Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells

Prolonged oxidative stress favors tumorigenic environment and inflammation. Oxidative stress may trigger redox adaptation mechanism(s) in tumor cells but not normal cells. This may increase levels of intracellular antioxidants and establish a new redox homeostasis. Nrf-2, a master regulator of batte...

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Detalles Bibliográficos
Autores principales: Patwardhan, Raghavendra S., Checker, Rahul, Sharma, Deepak, Sandur, Santosh K., Sainis, Krishna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679038/
https://www.ncbi.nlm.nih.gov/pubmed/23776571
http://dx.doi.org/10.1371/journal.pone.0065929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679038/
https://www.ncbi.nlm.nih.gov/pubmed/23776571
http://dx.doi.org/10.1371/journal.pone.0065929

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