HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

The nature of the cellular and molecular mechanisms for the transition of avascular cartilage replacement with bone during endochondral ossification remains poorly understood. One of the driving forces is hypoxia. As a master regulator of hypoxia, hypoxia-inducible factor-1α (HIF-1α) has been report...

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Detalles Bibliográficos
Autores principales: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Wu, Chengai, Xing, Yonggang, Zou, Xuenong, Tian, Wei, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://www.ncbi.nlm.nih.gov/pubmed/23776575
http://dx.doi.org/10.1371/journal.pone.0065940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679053/
https://www.ncbi.nlm.nih.gov/pubmed/23776575
http://dx.doi.org/10.1371/journal.pone.0065940

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