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Epitope Mapping of M36, a Human Antibody Domain with Potent and Broad HIV-1 Inhibitory Activity

M36 is the first member of a novel class of potent HIV-1 entry inhibitors based on human engineered antibody domains (eAds). It exhibits broad inhibitory activity suggesting that its CD4-induced epitope is highly conserved. Here, we describe fine mapping of its epitope by using several approaches. F...

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Detalles Bibliográficos
Autores principales:	Wan, Chao, Sun, Jianping, Chen, Weizao, Yuan, Xiaohui, Chong, Huihui, Prabakaran, Ponraj, Dimitrov, Dimiter S., He, Yuxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679054/ https://www.ncbi.nlm.nih.gov/pubmed/23776690 http://dx.doi.org/10.1371/journal.pone.0066638

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