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Imaging Proteolytic Activity in Live Cells and Animal Models

In addition to their degradative role in protein turnover, proteases play a key role as positive or negative regulators of signal transduction pathways and therefore their dysregulation contributes to many disease states. Regulatory roles of proteases include their hormone-like role in triggering G...

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Detalles Bibliográficos
Autores principales: Galbán, Stefanie, Jeon, Yong Hyun, Bowman, Brittany M., Stevenson, James, Sebolt, Katrina A., Sharkey, Lisa M., Lafferty, Michael, Hoff, Benjamin A., Butler, Braeden L., Wigdal, Susan S., Binkowski, Brock F., Otto, Paul, Zimmerman, Kris, Vidugiris, Gediminas, Encell, Lance P., Fan, Frank, Wood, Keith V., Galbán, Craig J., Ross, Brian D., Rehemtulla, Alnawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679058/
https://www.ncbi.nlm.nih.gov/pubmed/23776643
http://dx.doi.org/10.1371/journal.pone.0066248