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Imaging Proteolytic Activity in Live Cells and Animal Models
In addition to their degradative role in protein turnover, proteases play a key role as positive or negative regulators of signal transduction pathways and therefore their dysregulation contributes to many disease states. Regulatory roles of proteases include their hormone-like role in triggering G...
Autores principales: | Galbán, Stefanie, Jeon, Yong Hyun, Bowman, Brittany M., Stevenson, James, Sebolt, Katrina A., Sharkey, Lisa M., Lafferty, Michael, Hoff, Benjamin A., Butler, Braeden L., Wigdal, Susan S., Binkowski, Brock F., Otto, Paul, Zimmerman, Kris, Vidugiris, Gediminas, Encell, Lance P., Fan, Frank, Wood, Keith V., Galbán, Craig J., Ross, Brian D., Rehemtulla, Alnawaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679058/ https://www.ncbi.nlm.nih.gov/pubmed/23776643 http://dx.doi.org/10.1371/journal.pone.0066248 |
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