Kindlin-1 Regulates Integrin Dynamics and Adhesion Turnover

Loss-of-function mutations in the gene encoding the integrin co-activator kindlin-1 cause Kindler syndrome. We report a novel kindlin-1-deficient keratinocyte cell line derived from a Kindler syndrome patient. Despite the expression of kindlin-2, the patient’s cells display several hallmarks related...

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Detalles Bibliográficos
Autores principales: Margadant, Coert, Kreft, Maaike, Zambruno, Giovanna, Sonnenberg, Arnoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679067/
https://www.ncbi.nlm.nih.gov/pubmed/23776470
http://dx.doi.org/10.1371/journal.pone.0065341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679067/
https://www.ncbi.nlm.nih.gov/pubmed/23776470
http://dx.doi.org/10.1371/journal.pone.0065341

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