Ligand Binding and Signaling of Dendritic Cell Immunoreceptor (DCIR) Is Modulated by the Glycosylation of the Carbohydrate Recognition Domain

C-type lectins are innate receptors expressed on antigen-presenting cells that are involved in the recognition of glycosylated pathogens and self-glycoproteins. Upon ligand binding, internalization and/or signaling often occur. Little is known on the glycan specificity and ligands of the Dendritic C...

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Detalles Bibliográficos
Autores principales: Bloem, Karien, Vuist, Ilona M., van der Plas, Arend-Jan, Knippels, Léon M. J., Garssen, Johan, García-Vallejo, Juan J., van Vliet, Sandra J., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679074/
https://www.ncbi.nlm.nih.gov/pubmed/23776650
http://dx.doi.org/10.1371/journal.pone.0066266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679074/
https://www.ncbi.nlm.nih.gov/pubmed/23776650
http://dx.doi.org/10.1371/journal.pone.0066266

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