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Distribution of Recombination Hotspots in the Human Genome – A Comparison of Computer Simulations with Real Data
Recombination is the main cause of genetic diversity. Thus, errors in this process can lead to chromosomal abnormalities. Recombination events are confined to narrow chromosome regions called hotspots in which characteristic DNA motifs are found. Genomic analyses have shown that both recombination h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679075/ https://www.ncbi.nlm.nih.gov/pubmed/23776462 http://dx.doi.org/10.1371/journal.pone.0065272 |