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Distribution of Recombination Hotspots in the Human Genome – A Comparison of Computer Simulations with Real Data

Recombination is the main cause of genetic diversity. Thus, errors in this process can lead to chromosomal abnormalities. Recombination events are confined to narrow chromosome regions called hotspots in which characteristic DNA motifs are found. Genomic analyses have shown that both recombination h...

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Detalles Bibliográficos
Autores principales: Mackiewicz, Dorota, de Oliveira, Paulo Murilo Castro, Moss de Oliveira, Suzana, Cebrat, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679075/
https://www.ncbi.nlm.nih.gov/pubmed/23776462
http://dx.doi.org/10.1371/journal.pone.0065272