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Analysis of Epigenetic Factors in Mouse Embryonic Neural Stem Cells Exposed to Hyperglycemia

BACKGROUND: Maternal diabetes alters gene expression leading to neural tube defects (NTDs) in the developing brain. The mechanistic pathways that deregulate the gene expression remain unknown. It is hypothesized that exposure of neural stem cells (NSCs) to high glucose/hyperglycemia results in activ...

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Detalles Bibliográficos
Autores principales: Shyamasundar, Sukanya, Jadhav, Shweta P., Bay, Boon Huat, Tay, Samuel Sam Wah, Kumar, S. Dinesh, Rangasamy, Danny, Dheen, S. Thameem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679101/
https://www.ncbi.nlm.nih.gov/pubmed/23776576
http://dx.doi.org/10.1371/journal.pone.0065945