Cargando…

Elevated Levels of CD4(+)CD25(+)FoxP3(+) T Cells in Systemic Sclerosis Patients Contribute to the Secretion of IL-17 and Immunosuppression Dysfunction

OBJECTIVE: Immune imbalance between regulatory T (Treg) and Th17 cells is a characteristic of systemic sclerosis (SSc). The functional heterogeneity among Treg can be elucidated by separating Treg into different subsets based on the expression of FoxP3 and CD45RA. The aim of this study was to invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xinjuan, Gao, Na, Li, Mengtao, Xu, Dong, Hou, Yong, Wang, Qian, Zhang, Guohua, Sun, Qiuning, Zhang, Henghui, Zeng, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679128/ https://www.ncbi.nlm.nih.gov/pubmed/23776439 http://dx.doi.org/10.1371/journal.pone.0064531

Ejemplares similares

HSP70 Enhances Immunosuppressive Function of CD4(+)CD25(+)FoxP3(+) T Regulatory Cells and Cytotoxicity in CD4(+)CD25(−) T Cells
por: Wachstein, Julian, et al.
Publicado: (2012)

The effects of trastuzumab on the CD4+CD25+FoxP3+ and CD4+IL17A+ T-cell axis in patients with breast cancer
por: Horlock, C, et al.
Publicado: (2009)

CD4(+)CD25(high)FoxP3(+) Regulatory T-cells in Hematologic Diseases
por: Moon, Hee-Won, et al.
Publicado: (2011)

Scolopendra subspinipes mutilans L. Koch Ameliorates Rheumatic Heart Disease by Affecting Relative Percentages of CD4(+)CD25(+)FoxP3 Treg and CD4(+)IL17 T Cells
por: Jiang, Tiechao, et al.
Publicado: (2019)

Functional defects in CD4(+) CD25(high) FoxP3(+) regulatory cells in ankylosing spondylitis
por: Guo, Huifang, et al.
Publicado: (2016)

Coexpression of CD25 and CD27 identifies FoxP3(+) regulatory T cells in inflamed synovia
por: Ruprecht, Claudia R., et al.
Publicado: (2005)

Numerical status of CD4(+)CD25(+)FoxP3(+) and CD8(+)CD28(-) regulatory T cells in multiple sclerosis
por: Kouchaki, Ebrahim, et al.
Publicado: (2014)

Retracted: Scolopendra subspinipes mutilans L. Koch Ameliorates Rheumatic Heart Disease by Affecting Relative Percentages of CD4(+)CD25(+)FoxP3 Treg and CD4(+)IL17 T Cells
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2021)

Apoptosis Signaling Is Altered in CD4(+)CD25(+)FoxP3(+) T Regulatory Lymphocytes in Pre-Eclampsia
por: Darmochwal-Kolarz, Dorota, et al.
Publicado: (2012)

The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway
por: Ohta, Akio, et al.
Publicado: (2012)

Evaluation of CD4+ CD25+ FoxP3+ Regulatory T cells and FoxP3 and CTLA-4 gene Expression in Patients wwith Newly Diagnosed Tuberculosis in Northeast of Iran
por: Ghazalsofala, Roghayeh, et al.
Publicado: (2015)

CD4(+)CD25(+)FoxP3(+) regulatory T cells and cytokines interact with estradiol in cases of missed abortion
por: CAO, WEIPING, et al.
Publicado: (2014)

IL-4Rα signaling in CD4(+)CD25(+)FoxP3(+) T regulatory cells restrains airway inflammation via limiting local tissue IL-33
por: Khumalo, Jermaine, et al.
Publicado: (2020)

Role of CD4(+)CD25(hi)CD127(lo/-)FoxP3(+) regulatory T lymphocytes in the pathogenesis of Behçet’s disease in children
por: Tran, TA, et al.
Publicado: (2011)

Idd9.1 Locus Controls the Suppressive Activity of FoxP3(+)CD4(+)CD25(+) Regulatory T-Cells
por: Yamanouchi, Jun, et al.
Publicado: (2010)

Serial Changes of CD4+CD25+FoxP3+ Regulatory T Cell in Canine Model of Sepsis Induced by Endotoxin
por: YU, Dohyeon, et al.
Publicado: (2014)

T Regulatory CD4(+)CD25(+)FoxP3(+) Lymphocytes in the Peripheral Blood of Left-Sided Colorectal Cancer Patients
por: Dylag-Trojanowska, Katarzyna, et al.
Publicado: (2019)

4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4(+)CD25(+)FoxP3(+) T Regulatory Cell Suppression
por: Barsoumian, Hampartsoum B., et al.
Publicado: (2016)

TLR-2 Signaling Promotes IL-17A Production in CD4(+)CD25(+)Foxp3(+) Regulatory Cells during Oropharyngeal Candidiasis
por: Bhaskaran, Natarajan, et al.
Publicado: (2015)

CD4(+)CD25(high)CD127(low/-)FoxP(3)(+) Regulatory T-Cell Population in Acute Leukemias: A Review of the Literature
por: Niedźwiecki, M., et al.
Publicado: (2019)

Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells
por: Wirsdörfer, Florian, et al.
Publicado: (2014)

Specialized dendritic cells induce tumor-promoting IL-10(+)IL-17(+) FoxP3(neg) regulatory CD4(+) T cells in pancreatic carcinoma
por: Barilla, Rocky M., et al.
Publicado: (2019)

The Expansion of CD25(high)IL-10(high)FoxP3(high) B Regulatory Cells Is in Association with SLE Disease Activity
por: Vadasz, Zahava, et al.
Publicado: (2015)

Association of CD4(+)CD25(+)FoxP3(+) regulatory T cells with natural course of childhood chronic immune thrombocytopenic purpura
por: Son, Bo Ra, et al.
Publicado: (2015)

A New Immunosuppressive Molecule Emodin Induces both CD4(+)FoxP3(+) and CD8(+)CD122(+) Regulatory T Cells and Suppresses Murine Allograft Rejection
por: Qiu, Feifei, et al.
Publicado: (2017)

Characteristics and PD-1 expression of peripheral CD4(+)CD127(lo)CD25(hi)FoxP3(+ )Treg cells in chronic HCV infected-patients
por: Shen, Tao, et al.
Publicado: (2011)

FoxP3(+) and IL-17(+) cells are correlated with improved prognosis in cervical adenocarcinoma
por: Punt, Simone, et al.
Publicado: (2015)

Identification, frequency, activation and function of CD4+ CD25(high)FoxP3+ regulatory T cells in children with juvenile idiopathic arthritis
por: Stelmaszczyk-Emmel, Anna, et al.
Publicado: (2011)

CD4+CD25+CD127-Foxp3+ and CD8+CD28- Tregs in Renal Transplant Recipients: Phenotypic Patterns, Association With Immunosuppressive Drugs, and Interaction With Effector CD8+ T Cells and CD19+IL-10+ Bregs
por: Aly, Mostafa G., et al.
Publicado: (2021)

Corrigendum: A New Immunosuppressive Molecule Emodin Induces both CD4(+)FoxP3(+) and CD8(+)CD122(+) Regulatory T Cells and Suppresses Murine Allograft Rejection
por: Qiu, Feifei, et al.
Publicado: (2020)

Increased CD4(+)CD45RA(-)FoxP3(low) cells alter the balance between Treg and Th17 cells in colitis mice
por: Ma, Ya-Hui, et al.
Publicado: (2016)

Identification of a FOXP3(+)CD3(+)CD56(+) population with immunosuppressive function in cancer tissues of human hepatocellular carcinoma
por: Li, Xiaofeng, et al.
Publicado: (2015)

Induction of IL-10 and TGFβ from CD4(+)CD25(+)FoxP3(+) T Cells Correlates with Parasite Load in Indian Kala-azar Patients Infected with Leishmania donovani
por: Bhattacharya, Pradyot, et al.
Publicado: (2016)

FoxP3(+) regulatory CD4 T cells control the generation of functional CD8 memory
por: de Goër de Herve, M.G., et al.
Publicado: (2012)

Plasmodium vivax: Induction of CD4(+)CD25(+)FoxP3(+) Regulatory T Cells during Infection Are Directly Associated with Level of Circulating Parasites
por: Bueno, Lilian Lacerda, et al.
Publicado: (2010)

The CD4+CD25+FoxP3+ Regulatory T Cells Regulated by MSCs Suppress Plasma Cells in a Mouse Model of Allergic Rhinitis
por: Restimulia, Lia, et al.
Publicado: (2021)

CD4(+)CD25(high)CD127(low/−)FoxP(3)(+) Regulatory T Cell Subpopulations in the Bone Marrow and Peripheral Blood of Children with ALL: Brief Report
por: Niedźwiecki, M., et al.
Publicado: (2018)

Photobiomodulation Therapy Restores IL-10 Secretion in a Murine Model of Chronic Asthma: Relevance to the Population of CD4(+)CD25(+)Foxp3(+) Cells in Lung
por: de Brito, Aurileia Aparecida, et al.
Publicado: (2022)

Immune Tolerance of Human Dental Pulp-Derived Mesenchymal Stem Cells Mediated by CD4(+)CD25(+)FoxP3(+) Regulatory T-Cells and Induced by TGF-β1 and IL-10
por: Hong, Jong Won, et al.
Publicado: (2017)

Androgen receptor modulates Foxp3 expression in CD4(+)CD25(+)Foxp3(+) regulatory T-cells
por: Walecki, Magdalena, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jfv6ggkuerv70jufpt6vj9psmu