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Shaping T Cell – B Cell Collaboration in the Response to Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 by Peptide Priming

Prime-boost vaccination regimes have shown promise for obtaining protective immunity to HIV. Poorly understood mechanisms of cellular immunity could be responsible for improved humoral responses. Although CD4+ T-cell help promotes B-cell development, the relationship of CD4+ T-cell specificity to an...

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Detalles Bibliográficos
Autores principales: Steede, N. Kalaya, Rust, Blake J., Hossain, Mohammad M., Freytag, Lucy C., Robinson, James E., Landry, Samuel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679139/
https://www.ncbi.nlm.nih.gov/pubmed/23776539
http://dx.doi.org/10.1371/journal.pone.0065748