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Early Proliferation Does Not Prevent the Loss of Oligodendrocyte Progenitor Cells during the Chronic Phase of Secondary Degeneration in a CNS White Matter Tract

Partial injury to the central nervous system (CNS) is exacerbated by additional loss of neurons and glia via toxic events known as secondary degeneration. Using partial transection of the rat optic nerve (ON) as a model, we have previously shown that myelin decompaction persists during secondary deg...

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Detalles Bibliográficos
Autores principales: Payne, Sophie C., Bartlett, Carole A., Savigni, Donna L., Harvey, Alan R., Dunlop, Sarah A., Fitzgerald, Melinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679191/
https://www.ncbi.nlm.nih.gov/pubmed/23776532
http://dx.doi.org/10.1371/journal.pone.0065710