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Early Proliferation Does Not Prevent the Loss of Oligodendrocyte Progenitor Cells during the Chronic Phase of Secondary Degeneration in a CNS White Matter Tract
Partial injury to the central nervous system (CNS) is exacerbated by additional loss of neurons and glia via toxic events known as secondary degeneration. Using partial transection of the rat optic nerve (ON) as a model, we have previously shown that myelin decompaction persists during secondary deg...
Autores principales: | Payne, Sophie C., Bartlett, Carole A., Savigni, Donna L., Harvey, Alan R., Dunlop, Sarah A., Fitzgerald, Melinda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679191/ https://www.ncbi.nlm.nih.gov/pubmed/23776532 http://dx.doi.org/10.1371/journal.pone.0065710 |
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