Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

AcrB is an inner membrane resistance-nodulation-cell division efflux pump and is part of the AcrAB–TolC tripartite efflux system. We have determined the crystal structure of AcrB with bound Linezolid at a resolution of 3.5 Å. The structure shows that Linezolid binds to the A385/F386 loops of the sym...

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Detalles Bibliográficos
Autores principales: Hung, Li-Wei, Kim, Heung-Bok, Murakami, Satoshi, Gupta, Goutam, Kim, Chang-Yub, Terwilliger, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679416/
https://www.ncbi.nlm.nih.gov/pubmed/23673416
http://dx.doi.org/10.1007/s10969-013-9154-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679416/
https://www.ncbi.nlm.nih.gov/pubmed/23673416
http://dx.doi.org/10.1007/s10969-013-9154-x

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