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Mahogunin ring finger-1 (MGRN1) Suppresses Chaperone-Associated Misfolded Protein Aggregation and Toxicity
Impairment in the elimination of misfolded proteins generates cellular toxicity and leads to various late-onset neurodegenerative diseases. However, the mechanisms by which cells recognize abnormal cellular proteins for selective clearance remain unknown. Lack of the mahogunin ring finger-1 (MGRN1)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679506/ https://www.ncbi.nlm.nih.gov/pubmed/23756845 http://dx.doi.org/10.1038/srep01972 |