p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts

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Cancer-associated fibroblasts (CAFs), the most abundant and probably the most active cellular component of breast cancer-associated stroma, promote carcinogenesis through paracrine effects; however, the molecular basis remains elusive. We have shown here that p16(INK4A) expression is reduced in 83%...

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Detalles Bibliográficos
Autores principales: Al-Ansari, M M, Hendrayani, S F, Shehata, A I, Aboussekhra, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679618/
https://www.ncbi.nlm.nih.gov/pubmed/22751126
http://dx.doi.org/10.1038/onc.2012.270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679618/
https://www.ncbi.nlm.nih.gov/pubmed/22751126
http://dx.doi.org/10.1038/onc.2012.270

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