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p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts
Cancer-associated fibroblasts (CAFs), the most abundant and probably the most active cellular component of breast cancer-associated stroma, promote carcinogenesis through paracrine effects; however, the molecular basis remains elusive. We have shown here that p16(INK4A) expression is reduced in 83%...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679618/ https://www.ncbi.nlm.nih.gov/pubmed/22751126 http://dx.doi.org/10.1038/onc.2012.270 |
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