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Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

BACKGROUND: Fragile X syndrome (FXS) is a common inherited form of intellectual disability caused by loss of function of the fragile X mental retardation protein. Recent animal studies suggest that upregulated downstream signaling by metabotropic glutamate receptor 5 (mGluR5) might be an important m...

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Detalles Bibliográficos
Autores principales: Lohith, Talakad G, Osterweil, Emily K, Fujita, Masahiro, Jenko, Kimberly J, Bear, Mark F, Innis, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679853/
https://www.ncbi.nlm.nih.gov/pubmed/23706040
http://dx.doi.org/10.1186/2040-2392-4-15