The binding characteristics of isoniazid with copper–zinc superoxide dismutase and its effect on enzymatic activity

BACKGROUND: Isoniazid (INH) is front-line anti-tuberculosis (TB) drugs, which are usually prescribed to TB patients for a total period of 6 months. Antituberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse reaction of TB treatment. It is reported that INH-induced hepatotoxicity is ass...

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Detalles Bibliográficos
Autores principales: Du, Nana, Sheng, Liangquan, Liu, Zhaodi, Hu, Xiaojuan, Xu, Huajie, Chen, Shuisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679938/
https://www.ncbi.nlm.nih.gov/pubmed/23738738
http://dx.doi.org/10.1186/1752-153X-7-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679938/
https://www.ncbi.nlm.nih.gov/pubmed/23738738
http://dx.doi.org/10.1186/1752-153X-7-97

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