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The binding characteristics of isoniazid with copper–zinc superoxide dismutase and its effect on enzymatic activity
BACKGROUND: Isoniazid (INH) is front-line anti-tuberculosis (TB) drugs, which are usually prescribed to TB patients for a total period of 6 months. Antituberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse reaction of TB treatment. It is reported that INH-induced hepatotoxicity is ass...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679938/ https://www.ncbi.nlm.nih.gov/pubmed/23738738 http://dx.doi.org/10.1186/1752-153X-7-97 |