The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding

BACKGROUND: High fat feeding increases hepatic fat accumulation and is associated with hepatic insulin resistance. AMP Activated Protein Kinase (AMPK) is thought to inhibit lipid synthesis by the acute inhibition of glycerol-3-phosphate acyltransferase (GPAT) activity and transcriptional regulation...

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Detalles Bibliográficos
Autores principales: Henriksen, Bradley S, Curtis, Mary E, Fillmore, Natasha, Cardon, Brandon R, Thomson, David M, Hancock, Chad R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679947/
https://www.ncbi.nlm.nih.gov/pubmed/23725555
http://dx.doi.org/10.1186/1758-5996-5-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679947/
https://www.ncbi.nlm.nih.gov/pubmed/23725555
http://dx.doi.org/10.1186/1758-5996-5-29

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