Organization and characterization of a biosynthetic gene cluster for bafilomycin from Streptomyces griseus DSM 2608

Streptomyces griseus DSM 2608 produces bafilomycin, an antifungal plecomacrolide antibiotic. We cloned and sequenced an 87.4-kb region, including a polyketide synthase (PKS) region, methoxymalonate genes, flavensomycinate genes, and other putative regulatory genes. The 58.5kb of PKS region consistin...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Yoon, Kim, Hyo Sun, Kim, Soo Hee, Oh, Hye Ryeung, Nam, Doo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679948/
https://www.ncbi.nlm.nih.gov/pubmed/23663353
http://dx.doi.org/10.1186/2191-0855-3-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679948/
https://www.ncbi.nlm.nih.gov/pubmed/23663353
http://dx.doi.org/10.1186/2191-0855-3-24

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