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Organization and characterization of a biosynthetic gene cluster for bafilomycin from Streptomyces griseus DSM 2608

Streptomyces griseus DSM 2608 produces bafilomycin, an antifungal plecomacrolide antibiotic. We cloned and sequenced an 87.4-kb region, including a polyketide synthase (PKS) region, methoxymalonate genes, flavensomycinate genes, and other putative regulatory genes. The 58.5kb of PKS region consistin...

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Detalles Bibliográficos
Autores principales:	Hwang, Jae Yoon, Kim, Hyo Sun, Kim, Soo Hee, Oh, Hye Ryeung, Nam, Doo Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679948/ https://www.ncbi.nlm.nih.gov/pubmed/23663353 http://dx.doi.org/10.1186/2191-0855-3-24

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