Modeling mutant phenotypes and oscillatory dynamics in the Saccharomyces cerevisiae cAMP-PKA pathway

Background The cyclic AMP-Protein Kinase A (cAMP-PKA) pathway is an evolutionarily conserved signal transduction mechanism that regulates cellular growth and differentiation in animals and fungi. We present a mathematical model that recapitulates the short-term and long-term dynamics of this pathway...

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Detalles Bibliográficos
Autores principales: Gonzales, Kevin, Kayıkçı, Ömür, Schaeffer, David G, Magwene, Paul M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679983/
https://www.ncbi.nlm.nih.gov/pubmed/23680078
http://dx.doi.org/10.1186/1752-0509-7-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679983/
https://www.ncbi.nlm.nih.gov/pubmed/23680078
http://dx.doi.org/10.1186/1752-0509-7-40

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