The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC

BACKGROUND: CSIC (5-chloro-3-phenylsulfonylindole-2-carboxamide), a non-nucleoside reverse transcriptase inhibitor (NNRTI) has not been advanced as a therapeutic anti-HIV candidate drug due to its low aqueous solubility and poor bioavailability. OBJECTIVE: The objective of this work was to formulate...

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Detalles Bibliográficos
Autores principales: Obitte, Nicholas C, Rohan, Lisa C, Adeyeye, Christianah M, Parniak, Michael A, Esimone, Charles O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680009/
https://www.ncbi.nlm.nih.gov/pubmed/23721408
http://dx.doi.org/10.1186/1742-6405-10-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680009/
https://www.ncbi.nlm.nih.gov/pubmed/23721408
http://dx.doi.org/10.1186/1742-6405-10-14

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