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Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact form

Dietary polyunsaturated fatty acids (PUFA), especially eicosapentaenoic acid (EPA), improve lipid metabolism and contribute to the prevention of vascular diseases such as atherosclerosis. However, EPA in the diet is easily oxidized at room temperature and several types of oxidized EPA (OEPA) derivat...

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Detalles Bibliográficos
Autores principales: Nanthirudjanar, Tharnath, Furumoto, Hidehiro, Hirata, Takashi, Sugawara, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680052/
https://www.ncbi.nlm.nih.gov/pubmed/23680128
http://dx.doi.org/10.1186/1476-511X-12-73