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Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact form
Dietary polyunsaturated fatty acids (PUFA), especially eicosapentaenoic acid (EPA), improve lipid metabolism and contribute to the prevention of vascular diseases such as atherosclerosis. However, EPA in the diet is easily oxidized at room temperature and several types of oxidized EPA (OEPA) derivat...
Autores principales: | Nanthirudjanar, Tharnath, Furumoto, Hidehiro, Hirata, Takashi, Sugawara, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680052/ https://www.ncbi.nlm.nih.gov/pubmed/23680128 http://dx.doi.org/10.1186/1476-511X-12-73 |
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