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Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

BACKGROUND: The modular design of synthetic gene circuits via composable parts (DNA segments) and pools of signal carriers (molecules such as RNA polymerases and ribosomes) has been successfully applied to bacterial systems. However, eukaryotic cells are becoming a preferential host for new syntheti...

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Detalles Bibliográficos
Autores principales: Marchisio, Mario Andrea, Colaiacovo, Moreno, Whitehead, Ellis, Stelling, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680069/
https://www.ncbi.nlm.nih.gov/pubmed/23705868
http://dx.doi.org/10.1186/1752-0509-7-42