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Identification of thresholds for dichotomizing DNA methylation data
DNA methylation plays an important role in many biological processes by regulating gene expression. It is commonly accepted that turning on the DNA methylation leads to silencing of the expression of the corresponding genes. While methylation is often described as a binary on-off signal, it is typic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680080/ https://www.ncbi.nlm.nih.gov/pubmed/23742247 http://dx.doi.org/10.1186/1687-4153-2013-8 |