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Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro

BACKGROUND: Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not protect LDL from oxidation in vitro, but is in fact oxidized fastest of all lipoproteins due to its rich polyunsaturated fatty a...

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Detalles Bibliográficos
Autores principales: Solakivi, Tiina, Kunnas, Tarja, Jaakkola, Olli, Renko, Jaana, Lehtimäki, Terho, Nikkari, Seppo T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680190/
https://www.ncbi.nlm.nih.gov/pubmed/23721366
http://dx.doi.org/10.1186/1476-511X-12-80