Cargando…

Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro

BACKGROUND: Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. We have previously shown that HDL does not protect LDL from oxidation in vitro, but is in fact oxidized fastest of all lipoproteins due to its rich polyunsaturated fatty a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Solakivi, Tiina, Kunnas, Tarja, Jaakkola, Olli, Renko, Jaana, Lehtimäki, Terho, Nikkari, Seppo T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680190/ https://www.ncbi.nlm.nih.gov/pubmed/23721366 http://dx.doi.org/10.1186/1476-511X-12-80

Ejemplares similares

Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells
por: Solakivi, Tiina, et al.
Publicado: (2009)

Late-life coronary heart disease mortality of Finnish war veterans in the TAMRISK study, a 28-year follow-up
por: Kunnas, Tarja, et al.
Publicado: (2011)

Association of low‐density lipoprotein receptor‐related protein 1 rs11613352 and angiopoietin‐like 3 rs2131925 with hypertension in men—the Tampere adult population cardiovascular risk study
por: Kunnas, Tarja, et al.
Publicado: (2018)

Lipoprotein docosapentaenoic acid is associated with serum matrix metalloproteinase-9 concentration
por: Solakivi, Tiina, et al.
Publicado: (2005)

HDL enhances oxidation of LDL in vitro in both men and women
por: Solakivi, T, et al.
Publicado: (2005)

Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study
por: Kunnas, Tarja, et al.
Publicado: (2016)

NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study
por: Kunnas, Tarja, et al.
Publicado: (2015)

Contribution of syndecan-4 genetic variants to hypertension, the TAMRISK study
por: Kunnas, Tarja, et al.
Publicado: (2014)

Association of Zinc Finger, C3HC-Type Containing 1 (ZC3HC1) rs11556924 Genetic Variant With Hypertension in a Finnish Population, the TAMRISK Study
por: Kunnas, Tarja, et al.
Publicado: (2015)

Family history of hypertension enhances age-dependent rise in blood pressure, a 15-year follow-up, the Tampere adult population cardiovascular risk study
por: Kunnas, Tarja, et al.
Publicado: (2023)

Functional Inducible Nitric Oxide Synthase Gene Variants Associate With Hypertension: A Case–Control Study in a Finnish Population—The TAMRISK Study
por: Nikkari, Seppo T., et al.
Publicado: (2015)

Contribution of SLC7A1 genetic variant to hypertension, the TAMRISK study
por: Määttä, Kirsi, et al.
Publicado: (2013)

Variant rs6749447 (T > G) in the serine threonine kinase gene is associated with cardiovascular complications, the Tampere adult population cardiovascular risk study
por: Kunnas, Tarja, et al.
Publicado: (2021)

The gene variant for desmin rs1058261 may protect against combined cancer and cardiovascular death, the Tampere adult population cardiovascular risk study
por: Piesanen, Jaakko, et al.
Publicado: (2022)

Hematocrit value at early middle age predicts hypertension at late middle age; the Tampere adult population cardiovascular risk study, a 30-year follow-up
por: Piesanen, Jaakko, et al.
Publicado: (2023)

Periodic cohort health examinations in the TAMRISK study show untoward increases in body mass index and blood pressure during 15 years of follow-up
por: Kunnas, Tarja, et al.
Publicado: (2012)

Genetic Variant Coding for Iron Regulatory Protein HFE Contributes to Hypertension, the TAMRISK Study
por: Määttä, Kirsi M., et al.
Publicado: (2015)

Genetic variation in bone morphogenetic proteins family members (BMPs 2 and 4) and hypertension risk in middle-aged men: The TAMRISK study
por: Piesanen, Jaakko V.I., et al.
Publicado: (2017)

No Association of nineteenCOX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study
por: Lähteelä, Kati, et al.
Publicado: (2012)

Gln27Glu variant of Beta2-adrenoceptor gene affects male type fat accumulation in women
por: Kunnas, Tarja, et al.
Publicado: (2009)

Minor variant of rs 16827043 in the iron regulator hemojuvelin gene (HJV) contributes to hypertension: The TAMRISK study
por: Nikkari, Seppo T., et al.
Publicado: (2017)

COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study
por: Huuskonen, Kati H., et al.
Publicado: (2008)

Hepcidin is potential regulator for renin activity
por: Piesanen, Jaakko, et al.
Publicado: (2022)

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo
por: Wang, Jie, et al.
Publicado: (2018)

Comparison of Three Troponins as Predictors of Future Cardiovascular Events – Prospective Results from the FINRISK and BiomaCaRE Studies
por: Neumann, Johannes Tobias, et al.
Publicado: (2014)

Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice
por: He, Chengwei, et al.
Publicado: (2012)

Improved γ-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases
por: Zhang, Yao, et al.
Publicado: (2017)

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction
por: Martorelli Di Genova, Bruno, et al.
Publicado: (2019)

Delta-5-desaturase: A novel therapeutic target for cancer management
por: Pang, Lizhi, et al.
Publicado: (2021)

CYP1A2 polymorphism −1545C > T (rs2470890) is associated with increased side effects to clozapine
por: Viikki, Merja, et al.
Publicado: (2014)

Delta-9 fatty acid desaturase mutants display increased body size
por: Clark, James F., et al.
Publicado: (2018)

Dual expression of transgenic delta-5 and delta-6 desaturase in tilapia alters gut microbiota and enhances resistance to Vibrio vulnificus infection
por: Chiang, Keng-Yu, et al.
Publicado: (2020)

Production of eicosapentaenoic acid by application of a delta-6 desaturase with the highest ALA catalytic activity in algae
por: Shi, Haisu, et al.
Publicado: (2018)

The sphingolipid biosynthetic enzyme Sphingolipid delta8 desaturase is important for chilling resistance of tomato
por: Zhou, Ying, et al.
Publicado: (2016)

The effect of apolipoprotein E polymorphism on serum metabolome – a population-based 10-year follow-up study
por: Karjalainen, Juho-Pekka, et al.
Publicado: (2019)

Delta-6-desaturase (FADS2) inhibition and omega-3 fatty acids in skeletal muscle protein turnover
por: Brown, Katie M., et al.
Publicado: (2019)

Application of a delta-6 desaturase with α-linolenic acid preference on eicosapentaenoic acid production in Mortierella alpina
por: Shi, Haisu, et al.
Publicado: (2016)

Association of Delta-6-Desaturase Expression with Aggressiveness of Cancer, Diabetes Mellitus, and Multiple Sclerosis: A Narrative Review
por: Arshad, Zhila, et al.
Publicado: (2019)

Molecular mechanism of interaction between fatty acid delta 6 desaturase and acyl-CoA by computational prediction
por: Cui, Jie, et al.
Publicado: (2022)

Fatty acid profiles and Delta9 desaturase (stearoyl-CoA desaturase; SCD 1) expression in adipose tissue surrounding benign and malignant breast tumors
por: Sefidabi, Reyhaneh, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q5h1o5452rncve71t91r4inmld