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Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70

Up-regulation of heat shock protein 70 (HSP70) could be elicited primarily by heat in former studies, and this was proved to be associated with cancer progression. Burkitt's lymphoma is one of highly aggressive B-cell non-Hodgkin’s lymphoma and is one of the fastest growing human tumors. To inv...

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Detalles Bibliográficos
Autores principales: Fang, Xiaosheng, Jiang, Yujie, Feng, Lili, Chen, Haiping, Zhen, Changqing, Ding, Mei, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680239/
https://www.ncbi.nlm.nih.gov/pubmed/23706027
http://dx.doi.org/10.1186/1475-2867-13-48