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TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells

BACKGROUND: Odontoblasts are specialized cells that form dentin and they are believed to be sensors for tooth pain. Transforming growth factor-β1 (TGF-β1), a pro-inflammatory cytokine expressed early in odontoblasts, plays an important role in the immune response during tooth inflammation and infect...

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Detalles Bibliográficos
Autores principales: Utreras, Elias, Prochazkova, Michaela, Terse, Anita, Gross, Jacklyn, Keller, Jason, Iadarola, Michael J, Kulkarni, Ashok B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680294/
https://www.ncbi.nlm.nih.gov/pubmed/23668392
http://dx.doi.org/10.1186/1744-8069-9-24