Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells

BACKGROUND: Molecular targeted therapy has emerged as a promising treatment of Hepatocellular carcinoma (HCC). One potential target is the Src family Kinase (SFK). C-Src, a non-receptor tyrosine kinase is a critical link of multiple signal pathways that regulate proliferation, invasion, survival, me...

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Detalles Bibliográficos
Autores principales: Chang, Alex Y, Wang, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680296/
https://www.ncbi.nlm.nih.gov/pubmed/23721490
http://dx.doi.org/10.1186/1471-2407-13-267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680296/
https://www.ncbi.nlm.nih.gov/pubmed/23721490
http://dx.doi.org/10.1186/1471-2407-13-267

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