A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples

BACKGROUND: Growing evidence suggests that DNA methylation plays a role in tissue-specific differentiation. Current approaches to methylome analysis using enrichment with the methyl-binding domain protein (MBD) are restricted to large (≥1 μg) DNA samples, limiting the analysis of small tissue sample...

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Detalles Bibliográficos
Autores principales: Oliver, Verity F, Wan, Jun, Agarwal, Saurabh, Zack, Donald J, Qian, Jiang, Merbs, Shannath L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680319/
https://www.ncbi.nlm.nih.gov/pubmed/23759032
http://dx.doi.org/10.1186/1756-8935-6-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680319/
https://www.ncbi.nlm.nih.gov/pubmed/23759032
http://dx.doi.org/10.1186/1756-8935-6-17

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