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AMP-activated protein kinase regulates L-arginine mediated cellular responses

BACKGROUND: Our prior study revealed the loss in short-term L-Arginine (ARG) therapeutic efficacy after continuous exposure; resulting in tolerance development, mediated by endothelial nitric oxide synthase (eNOS) down-regulation, secondary to oxidative stress and induced glucose accumulation. Howev...

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Detalles Bibliográficos
Autores principales: Mohan, Srinidi, Patel, Harsh, Bolinaga1, Jorge, Soekamto, Nathania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680329/
https://www.ncbi.nlm.nih.gov/pubmed/23718875
http://dx.doi.org/10.1186/1743-7075-10-40