Tightly Regulated and Homogeneous Transgene Expression in Human Adipose-Derived Mesenchymal Stem Cells by Lentivirus with Tet-Off System

Genetic modification of human adipose tissue–derived multilineage progenitor cells (hADMPCs) is highly valuable for their exploitation in therapeutic applications. Here, we have developed a novel single tet-off lentiviral vector platform. This vector combines (1) a modified tetracycline (tet)-respon...

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Detalles Bibliográficos
Autores principales: Moriyama, Hiroyuki, Moriyama, Mariko, Sawaragi, Kei, Okura, Hanayuki, Ichinose, Akihiro, Matsuyama, Akifumi, Hayakawa, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680377/
https://www.ncbi.nlm.nih.gov/pubmed/23776652
http://dx.doi.org/10.1371/journal.pone.0066274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680377/
https://www.ncbi.nlm.nih.gov/pubmed/23776652
http://dx.doi.org/10.1371/journal.pone.0066274

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