Advanced Glycation End Products Induce Human Corneal Epithelial Cells Apoptosis through Generation of Reactive Oxygen Species and Activation of JNK and p38 MAPK Pathways

Advanced Glycation End Products (AGEs) has been implicated in the progression of diabetic keratopathy. However, details regarding their function are not well understood. In the present study, we investigated the effects of intracellular reactive oxygen species (ROS) and JNK, p38 MAPK on AGE-modified...

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Detalles Bibliográficos
Autores principales: Shi, Long, Yu, Xiaoming, Yang, Hongling, Wu, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680386/
https://www.ncbi.nlm.nih.gov/pubmed/23776698
http://dx.doi.org/10.1371/journal.pone.0066781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680386/
https://www.ncbi.nlm.nih.gov/pubmed/23776698
http://dx.doi.org/10.1371/journal.pone.0066781

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