Cargando…
Advanced Glycation End Products Induce Human Corneal Epithelial Cells Apoptosis through Generation of Reactive Oxygen Species and Activation of JNK and p38 MAPK Pathways
Advanced Glycation End Products (AGEs) has been implicated in the progression of diabetic keratopathy. However, details regarding their function are not well understood. In the present study, we investigated the effects of intracellular reactive oxygen species (ROS) and JNK, p38 MAPK on AGE-modified...
Autores principales: | Shi, Long, Yu, Xiaoming, Yang, Hongling, Wu, Xinyi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680386/ https://www.ncbi.nlm.nih.gov/pubmed/23776698 http://dx.doi.org/10.1371/journal.pone.0066781 |
Ejemplares similares
-
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
por: Pereira, Lorena, et al.
Publicado: (2013) -
Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways
por: Jiang, Zhongjia, et al.
Publicado: (2017) -
Matrine‐Type Alkaloids Inhibit Advanced Glycation End Products Induced Reactive Oxygen Species‐Mediated Apoptosis of Aortic Endothelial Cells In Vivo and In Vitro by Targeting MKK3 and p38MAPK Signaling
por: Liu, Zhongwei, et al.
Publicado: (2017) -
NADPH Oxidase 2-Derived Reactive Oxygen Species Mediate FFAs-Induced Dysfunction and Apoptosis of β-Cells via JNK, p38 MAPK and p53 Pathways
por: Yuan, Huiping, et al.
Publicado: (2010) -
Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways
por: Yang, Zhangshuo, et al.
Publicado: (2022)