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Augmented BMPRIA-Mediated BMP Signaling in Cranial Neural Crest Lineage Leads to Cleft Palate Formation and Delayed Tooth Differentiation

The importance of BMP receptor Ia (BMPRIa) mediated signaling in the development of craniofacial organs, including the tooth and palate, has been well illuminated in several mouse models of loss of function, and by its mutations associated with juvenile polyposis syndrome and facial defects in human...

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Detalles Bibliográficos
Autores principales: Li, Lu, Wang, Ying, Lin, Minkui, Yuan, Guohua, Yang, Guobin, Zheng, Yuqian, Chen, YiPing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680418/
https://www.ncbi.nlm.nih.gov/pubmed/23776616
http://dx.doi.org/10.1371/journal.pone.0066107