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Imbalance of SMC1 and SMC3 Cohesins Causes Specific and Distinct Effects
SMC1 and SMC3 form a high-affinity heterodimer, which provides an open backbone of the cohesin ring, to be closed by a kleisin protein. RNAi mediated knock-down of either one heterodimer partner, SMC1 or SMC3, is expected to cause very similar if not identical phenotypes. However, we observed highly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680458/ https://www.ncbi.nlm.nih.gov/pubmed/23776448 http://dx.doi.org/10.1371/journal.pone.0065149 |