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Dissecting the roles of ROCK isoforms in stress-induced cell detachment

The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1(−/−) and ROCK2(−/−) mice, we have recently reported that they play different roles in regulat...

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Detalles Bibliográficos
Autores principales: Shi, Jianjian, Surma, Michelle, Zhang, Lumin, Wei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680529/
https://www.ncbi.nlm.nih.gov/pubmed/23598717
http://dx.doi.org/10.4161/cc.24699