Cargando…
Dissecting the roles of ROCK isoforms in stress-induced cell detachment
The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1(−/−) and ROCK2(−/−) mice, we have recently reported that they play different roles in regulat...
Autores principales: | Shi, Jianjian, Surma, Michelle, Zhang, Lumin, Wei, Lei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680529/ https://www.ncbi.nlm.nih.gov/pubmed/23598717 http://dx.doi.org/10.4161/cc.24699 |
Ejemplares similares
-
Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment
por: Shi, Jianjian, et al.
Publicado: (2013) -
Fruitless isoforms and target genes specify the sexually dimorphic nervous system underlying Drosophila reproductive behavior
por: Nojima, Tetsuya, et al.
Publicado: (2014) -
The beneficial role of extracellular reactive oxygen species in apoptosis-induced compensatory proliferation
por: Diwanji, Neha, et al.
Publicado: (2016) -
ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment
por: Surma, Michelle, et al.
Publicado: (2014) -
Dissecting the Mechanisms of Doxorubicin and Oxidative Stress-Induced Cytotoxicity: The Involvement of Actin Cytoskeleton and ROCK1
por: Wei, Lei, et al.
Publicado: (2015)