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Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence

The FOXO family of transcription factors is central to the regulation of organismal longevity and cellular survival. Several studies have indicated that FOXO factors lie at the center of a complex network of upstream pathways, cofactors and downstream targets (FOXO-interaction networks), which may h...

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Detalles Bibliográficos
Autores principales: Parmentier, Frédéric, Lejeune, François-Xavier, Neri, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680703/
https://www.ncbi.nlm.nih.gov/pubmed/23781200
http://dx.doi.org/10.3389/fnagi.2013.00022